Royal College of Surgeons in Ireland Coláiste Ríoga na Máinleá in Éirinn

Department of Clinical Microbiology Research

 

The major research interests of the department are healthcare-associated infection (HCAI), including that caused by methicillin-resistant Staphylococcus aureus (MRSA), Vancomycin-resistant enterococci (VRE), Clostridium difficile and multi-drug resistant Gram-negative bacilli (extended-spectrum beta-lactamase (ESBL) producing enterobacteriaceae and Carbapenem-resistant enterobacteriaceae (CRE)).  We are interested in the surveillance, epidemiology and pathogenesis of these micro-organisms in infections such as wound infection, device-related infection and bloodstream infection. We investigate aspects of infection in settings such as cystic fibrosis and renal impairment. These studies underpin approaches to prevention, management and treatment of infections and help us to identify and evaluate novel approaches to patient care.  We are also interested in surveillance of the healthcare environment close to patients and seek to improve hospital hygiene and reduce HCAI rates through novel decontamination systems.  Another focus of our research is elucidating the role of non-coding RNA in host-pathogen interactions, sex-specific disease responses and innate immunity; we are also developing microRNA-based therapeutics for specific lung diseases.

We are committed to improving patient care through our research. Our strengths in achieving this are our collaborative approach and our combined expertise, which includes basic scientists, clinician scientists and clinical microbiologists