Royal College of Surgeons in Ireland Coláiste Ríoga na Máinleá in Éirinn

Available Research Projects

FUNDED PhD: Dr Finbarr Leacy - Biostatistics

The project seeks to find a highly motivated student to carry out a study focused on the evaluation of health policies in the Irish healthcare setting using state-of-the-art causal inference methods. The successful candidate will apply existing propensity score and instrumental variable approaches to nationally representative databases, cohort studies and disease registries; developing extensions of these approaches where necessary. More Information.


FUNDED PhD: Dr Simon Furney - Cancer Bioinformatics and Genomics

The project seeks to find a highly motivated student to carry out a study focused on the bioinformatic identification of mechanisms of tumour development and evolution from cancer genome sequencing data. The successful candidate will probe thousands of publicly available cancer genome sequences using existing and novel bioinformatics approaches. More Information.


FUNDED PhD: Dr Ian Kelleher - Psychiatric epidemiology

This is an exciting opportunity to complete a fully funded PhD by conducting new research into understanding the developmental trajectory from childhood to adulthood mental ill health. Using large European datasets, the PhD project will look at the evolution of mental disorders from childhood to adulthood, and investigate factors that contribute to recovery versus prolonged illness and disability. More Information.


FUNDED PhD: Dr Oran Kennedy - Arthritis, Joint Disease, Mechanobiology

The project seeks to find a highly motivated student to investigate the role of subchondral bone in post-traumatic osteoarthritis (PTOA), which typically affects a younger population (often highly active, such as athletes) compared with age-related osteoarthritis. The successful candidate will be based in the Tissue Engineering Research Group at RCSI applying novel approaches to detect PTOA progression and investigating drug delivery systems that will mitigate joint degeneration. More Information.


FUNDED PhD: Dr Marco Monopoli - nanomaterials

The project seeks to find a highly motivated student to carry out a study focused in obtaining a complete understanding of the mechanisms of interaction between nanomaterials and living systems essential for Nanomedicine, Nanotoxicology applications and to evaluate their Environmental Impact. More Information.


Exosomes trigger tumour neovascularisation and and subsequent escape from chemotherapy

Olga Piskareva, Molecular & Cellular Therapeutics. Keywords: cancer, neuroscience, drug resistance, angiogenesis, exosomes. More Information.


Network meta analysis of psychological factors influencing health behaviours

Frank Doyle, Psychology. Keywords: cancer, cardiovascular disorders, respiratory diseases, population health, gynaecology, obstetrics & perinatal health, network meta-analysis, health behaviours, psychological factors. More Information.


Depression and health behaviours in chronic conditions

Frank Doyle, Psychology. Keywords: cardiovascular disorders, respiratory diseases, population health, depression, behaviour change, adherence. More Information.


Adherence to inhaled therapies

Frank Doyle, Psychology. Keywords: respiratory diseases, inhaled therapy, adherence, behaviour change. More Information.


Psychometrics of patient reported outcomes

Frank Doyle, Psychology. Keywords: population health, patient reported outcomes, item response theory, psychometrics. More Information.


Provision of smoking cessation care in hospital settings

Frank Doyle, Psychology. Keywords: cancer, cardiovascular disorders, respiratory diseases, population health, medical education, smoking, behaviour change, medical education. More Information.


Attitudes to organ donation

Frank Doyle, Psychology. Keywords: population health, organ donation, attitudes, intervention. More Information.


Breast cancer microcalcification-induced local inflammation; potential consequences for tumour progression

Maria Morgan, Molecular & Cellular Therapeutics. Keywords: cancer, breast cancer, cell biology, immunology. More Information.


Automated flow micro-reactors and parallel microwave-assisted synthesis

Donal O'Shea, Pharmaceutical & Medicinal Chemistry. Keywords: pharmacy, pharmaceutical sciences & chemistry. More Information.


Mixed Li/K amides and enantioselective carbolithiations as effective synthetic tools

Donal O'Shea, Pharmaceutical & Medicinal Chemistry. Keywords: pharmacy, pharmaceutical sciences & chemistry. More Information.


New class of light activated anti-cancer and anti-microbial agents

Donal O'Shea, Pharmaceutical & Medicinal Chemistry. Keywords: cancer, pharmacy, pharmaceutical sciences & chemistry, photodynamic therapy (pdt), anti-cancer, anti-microbial. More Information.


New class of near-infrared (NIR) fluorochrome for real-time fluorescence guided surgery

Donal O'Shea, Pharmaceutical & Medicinal Chemistry. Keywords: pharmacy, pharmaceutical sciences & chemistry, nir fluorochrome, fluorochrome imaging, cancer. More Information.


Injectable chemotherapeutic gels for the treatment of glioblastoma multiforme

Eduardo Ruiz-Hernandez, Department of Anatomy and School of Pharmacy. Keywords: cancer, bioengineering, pharmacy, pharmaceutical sciences & chemistry, drug delivery systems, injectable gels, glioblastoma. More Information.


The Role of Platelets in Human Pregnancy: An exploration of the nature of the cytokine secretion profile during normal human pregnancy

Niamh Moran, Molecular & Cellular Therapeutics. Keywords: gynaecology, obstetrics & perinatal health, pregnancy, platelet, non-thrombotic. More Information.


Movement analysis of sports-related hip and groin pain

Helen French, School of Physiotherapy. Keywords: physiotherapy, 3D motion analysis, hip pain, movement screening. More Information.


The Role of Platelets in Cancer: An exploration of the nature of the cytokine secretion profile in during cancer progression

Niamh Moran, Molecular & Cellular Therapeutics. Keywords: cancer, cardiovascular disorders, platelet, metastasis More Information.


Novel peptidomimetics of Nature's antibiotics

Marc Devocelle, Pharmaceutical and Medicinal Chemistry. Keywords: Infection & Immunity, Peptidomimetics, Antimicrobial Peptides, Antibiotic resistance. More Information.


Nanomedicines against multi-drug resistant bacteria

Marc Devocelle, Pharmaceutical and Medicinal Chemistry. Keywords: Infection & Immunity, Antibiotic resistance, Antimicrobial Peptides, Prodrugs and nanomedicines. More Information.