Royal College of Surgeons in Ireland Coláiste Ríoga na Máinleá in Éirinn

Infection, Immunity & Inflammation

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RCSI research in these fields mainly focuses on the following areas of research

Microbial pathogenesis, antimicrobial resistance and malaria

Research in this area focuses specifically on the prevalence, epidemiology, pathogenesis and molecular characteristics of antibiotic resistant organisms that cause hospital infections. We are investigating novel decontamination methods and their impact on reducing hospital infections, as well as novel therapeutics. Malaria is a major global pathogen and research is this area focuses on the evaluation of potential new vaccines.

Host response to microbial infection

Research in this area has important implications for understanding the molecular mechanisms through which the host responds to invading microorganisms. Research focuses on the cardiovascular response to infection and how infection weakens bone and induces bone loss. Research in this area is also aligned with research in advanced biomaterials and focuses on novel biomaterials for infection control and tissue restoration.

Innate Immunity and its role in autoimmune and inflammatory disease

Research in this area focuses on the role innate immune mechanisms that recognize viral infections play in the initiation and pathology of inflammatory disorders such as herpes simplex keratitis (HSK). How mechanisms of innate immunity can be targeted for treatment of chronic intestinal disorders, such as inflammatory bowel disease, is also an area of research.

Senior Academics/Researchers in this area are listed below:


Hilary Humphreys

Clinical Microbiology

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Stephen Keely Molecular Medicine 

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Steve Kerrigan

School of Pharmacy

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Samuel McConkey  Department of International Health & Tropical Medicine View Samuel McConkey's profile

Kevin McGuigan

Physiology & Medical Physics

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Zena Moore  School of Nursing & Midwifery 

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Conor Murphy


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