Royal College of Surgeons in Ireland Coláiste Ríoga na Máinleá in Éirinn

Neurological and psychiatric disorders

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Neuroscience research at the RCSI encompasses the full spectrum of basic, translational and clinical research with particular emphasis on neurological disorders such as epilepsy and stroke, neurodegenerative diseases including amyotrophic lateral sclerosis, as well as psychiatric diseases such as schizophrenia and bipolar disorder.

Research approaches include single cell and in vivo molecular imaging; intracellular signalling cascades and computational analysis of pathways; discovery and delivery of neurotherapeutics; the genetic and epigenetic basis of epilepsy; the role of non-coding RNA (including microRNA) in neurological disorders; epidemiology, risk factors, neuropathology and biomarkers of brain diseases. Very active in this area are the RCSI Centre of System Medicine and Centre for Neurological Disorders .RCSI also play a leading role in EpiMiRNA, a large collaborative research programme funded by the European Commission, and the SFI-funded INFANT Centre. More information on the research centres and programmes in this area is available below.

Senior Academics/Researchers and Research Centres and Programmes in this area are listed below:

Gianpiero Cavalleri Molecular & Cellular Therapeutics View Gianpiero Cavalleri's profile
David Henshall Physiology & Medical Physics View David Henshall's profile
Jochen Prehn Physiology & Medical Physics View Jochen Prehn's profile
John Waddington Molecular & Cellular Therapeutics View John Waddington's profile
David Cotter Psychiatry View David Cotter's profile
Mary Cannon Psychiatry View Mary Cannon's profile
Kieran Murphy Psychiatry View Kieran Murphy's profile
Norman Delanty Molecular and Cellular Therapeutics View Norman Delanty's profile

Research Centres & Programmes in this Area


The EpimiRNA Consortium, involving 16 partners from 8 European countries, the USA and Brazil is funded from the European Union's Framework Programme 7 to investigate molecular mechanisms, diagnostics and treatments for epilepsy.

CSND Centre for the Study of Neurological Disorders

CSND is the only centre in Ireland devoted to the study of acute and chronic neurological disorders. The mission of the CSND is to advance fundamental knowledge of the basis of neurological disorders by conducting cutting edge research and by providing training to the next generation of scientists.

CSM Centre for Systems Medicine

The mission of the CSM is to undertake translational, multidisciplinary research that identifies proteins and genes implicated in human disease and utilizes systems biology and mathematical approaches in order to develop new prognostic tools for the treatment of cancer, neurological disorders and diabetes, and to develop more targeted therapies for patients.