Royal College of Surgeons in Ireland Coláiste Ríoga na Máinleá in Éirinn

Respiratory diseases

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RCSI research in respiratory diseases focuses on cystic fibrosis (CF), alpha-1 antitrypsin deficiency, Asthma and Chronic Obstructive Pulmonary Diseases (COPD).

Major research interests include pulmonary innate immunity, airway fluid dynamics in Alpha-1 antitrypsin deficiency, protease/anti protease interactions in the lung, signal transduction and gene regulation in bronchial epithelium, the role of the neutrophil in inflammatory lung disease, the role of estrogen and the CF gender gap, microRNA profiling in CF, pro-resolution and ion transport effects of lipoxins in CF, endoplasmic reticulum stress responses and anti-inflammatory and gene therapeutics.

A significant strength of RCSI research in respiratory diseases is its interactions with pharmaceutical companies interested in translational research. This synergy has led to clinical trials for emerging therapeutics for cystic fibrosis and alpha-1 antitrypsin deficiency and medical devices for monitoring COPD.

Senior Academics/Researchers and Research Centres and Programmes in this area are listed below:

PIDepartmentProfile
Aidan Bradford  Physiology & Medical Physics View Aiden Bradford's profile

Richard Costello

Medicine

View Richard Costello's profile

Catherine Greene

Medicine

View Catherine Greene's profile

Brian Harvey

Molecular Medicine

View Brian Harvey's profile

Noel G McElvaney

Medicine

View Noel G McElvaney's profile